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BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. A 78-year-old woman presents to the outpatient clinic for workup for depression. Medical history includes hypertension, simple partial seizures, and osteoporosis. The patient reports a
6.8 kg non-intentional weight loss over the past month. Home medications include lisinopril, hydrochlorothiazide, carbamazepine, and alendronate. The patient has been diagnosed with severe depression. Which antidepressant should be recommended for this patient?

A) Nortriptyline 25 mg daily
B) Mirtazapine 15 mg daily
C) Escitalopram 20 mg daily
D) Bupropion XL 150 mg daily

2. Many clinically important adverse drug reactions (ADRs) are detected after the marketing of a drug, rather than during premarketing clinical trials. Of the following, which is the primary reason for this phenomenon?

A) Too few patients are studied for too short a period of time during premarketing clinical trials.
B) Premarketing studies focus on efficacy rather than on safety; therefore, the study design accounts for the failure to detect ADRs.
C) Adverse reactions that are due to drug interactions or drug accumulation in renal insufficiency cannot be studied prospectively during the premarketing phase of clinical evaluation.
D) Pharmaceutical companies prefer to market agents with favorable side-effect profiles, so they focus premarketing studies on efficacy rather than on ADRs.

3. A hospital requests a policy and procedure document for the monitoring and reporting of significant adverse drug reactions. Which agency requires a policy for the reporting of adverse drug reactions by hospitals?

A) Institute for Safe medication Practices
B) National Committee for Quality Assurance
C) Joint Commission
D) Food and Drug Administration

4. A 35-year-old Woman is diagnosed with pustular psoriasis, which covers 35% of her body. She has tried high-potency topical steroid creams and topical coal tar with ultraviolet B treatments in the past, with no effect. Which of the following is the best therapeutic option for this patient?

A) Anthralin
B) Methotrexate
C) Halobetasol
D) Calcipotriene

5. A 47-year-old patient with end-stage renal disease undergoing hemodialysis has an HCT of 23% and exhibits anginal symptoms. Upon further Workup, no evidence of occult bleeding is found.
In addition to antianginal therapy, which of the following is the most appropriate initial treatment for this patient's anemia?

A) Subcutaneous erythropoietin
B) Iron dextran
C) Two units of PRBCs
D) Oral iron

Solutions: